Biomaterials and Biointerfaces

  • Bacteria hide in microcrack defects on the surface of silicone medical devices

    van den Berg, D.; Asker, D.; Awad, T.; Hatton, B. D. Mechanical deformation of elastomer medical devices can enable microbial surface colonization. Scientific Reports 2023, 13.

  • Non-fouling silicones for bacteria

    Lavielle, N.; Asker, D.; Hatton, B. D. Lubrication dynamics of swollen silicones to limit long term fouling and microbial biofilms. Soft Matter 2021, 17, 936.

  • Enzyme-modified catheters

    Asker, D.; Awad, T. S.; Raju, D.; Sanchez, H.; Lacdao, I.; Gilbert, S.; Sivarajah, P.; Andes, D. R.; Sheppard, D. C.; Howell, P. L., Hatton, B.D. Preventing Pseudomonas aeruginosa biofilms on indwelling catheters by surface-bound enzymes. ACS Applied Bio Materials 2021, 4 (12), 8248-8258.

  • Non-fouling silicones for antifouling

    Kimmins, K. M.; James, B. D.; Nguyen, M.-T.; Asker, D.; Hatton, B. D.; Sone, E. D. Oil-Infused Silicone Prevents Zebra Mussel Adhesion. ACS Applied Bio Materials 2019, 2 (12), 5841.

  • Surface-bound enzymes actively degrade bacterial biofilms

    Asker, D.; Baker, P.; Awad, T.; Howell, L.; Hatton, B. D., Non-eluting, surface-bound enzymes disrupt bacterial surface attachment through continuous polysaccharide degradation. Biomaterials 2018, 167, 168-176.

  • Bacteria-free food surfaces

    Awad, T.; Asker, D.; Hatton, B. D., Modification of stainless steel food processing surfaces to reduce bacterial biofilm growth. ACS Applied Materials and Interfaces 2018, 10 (27), 22902–22912.

  • Slippery surface design prevents blood clotting

    Leslie, D. C.; Waterhouse, A.; Berthet, J. B.; … Hatton, B. D.; et al. A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling. Nature Biotechnology 2014, 32, 1134.

  • Design of slippery silicones

    MacCallum, N.; Howell, C.; Kim, P.; Sun, D.; Friedlander, R.; …Hatton, B. D. et al. Liquid-infused silicone as a biofouling-free medical material. ACS Biomaterials Science & Engineering 2014, 1 (1), 43.

  • Stem cells on a bed of nails

    Bucaro, M. A.; Vasquez, Y.; Hatton, B. D.; Aizenberg, J. Fine-Tuning the Degree of Stem Cell Polarization and Alignment on Ordered Arrays of High-Aspect-Ratio Nanopillars. ACS nano 2012, 6 (7), 6222.